"My Sister’s Keeper" is a big downer of the movie but it is a useless downer, I think. And it features one character which I believe is despicable which I won’t reveal just yet. The movie deals with parents trying to deal with raising a daughter who has leukemia and doing whatever it takes to keep her alive. This sounds like a story about a family’s strength and resilience. In limited degree, some of that element is in the movie.